Molecular correlates of cerebellar mutism syndrome in medulloblastoma
نویسندگان
چکیده
منابع مشابه
Neurocognitive outcome 12 months following cerebellar mutism syndrome in pediatric patients with medulloblastoma.
The aim is to prospectively assess early neurocognitive outcome of children who developed cerebellar mutism syndrome (CMS) following surgical resection of a posterior fossa embryonal tumor, compared with carefully matched control patients. Children who were enrolled on an ongoing IRB-approved protocol for treatment of embryonal tumors, were diagnosed with postoperative CMS, and had completed pr...
متن کاملThe syndrome of 'cerebellar' mutism and subsequent dysarthria.
"Cerebellar" mutism refers to a specific childhood disorder in which a complete but transient loss of speech, followed by dysarthria, occurs after removal of a cerebellar tumor. We present a consecutive series of 15 children with this disorder, which we prefer to designate "mutism and subsequent dysarthria." The conditions in which it develops suggest also an extracerebellar component of cerebe...
متن کاملBilateral crossed cerebello-cerebral diaschisis and mutism after surgery for cerebellar medulloblastoma.
A 7-year-old boy developed mutism after surgery for cerebellar medulloblastoma. Postoperative magnetic resonance imaging (MRI) showed atrophy of the cerebellar vermis and both cerebellar hemispheres, predominantly on the right side. Single photon emission computed tomography (SPECT) with technetium-99m-ethyl cysteinate dimer (Tc-99m ECD) revealed decreased cerebral blood flow (CBF) in the bilat...
متن کاملNeuroanatomical Mechanism of Cerebellar Mutism After Stroke
Cerebellar mutism (CM) is a rare neurological condition characterized by lack of speech due to cerebellar lesions. CM is often reported in children. We describe a rare case of CM after spontaneous cerebellar hemorrhage. The patient showed mutism, irritability, decreased spontaneous movements and oropharyngeal apraxia. Diffusion tensor imaging revealed significant volume reduction of medial fron...
متن کاملCerebellar mutism following posterior fossa tumor resection in children.
AIM Cerebellar mutism is a documented complication of posterior fossa surgery in pediatric ages. Risk factors such as the type of tumor, size, and location of tumor, hyrdrocephalus, postoperative cerebellar swelling for cerebellar mutism were investigated in this study. MATERIAL AND METHODS A consecutive series of 32 children with a cerebellar tumor were operated on at the Haseki Educational ...
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ژورنال
عنوان ژورنال: Neuro-Oncology
سال: 2019
ISSN: 1522-8517,1523-5866
DOI: 10.1093/neuonc/noz158